Matador customer: E. coli illness ‘worst pain you could imagine’

A Seattle woman who became ill in the recent E. coli outbreak described it as the “worst pain you could imagine.”

king_annamarie_kirkpatrick_1473816059517_6036798_ver1-033-year-old Annamarie Kirkpatrick said she ate at Matador in Seattle’s Ballard neighborhood on August 20. She became ill with severe abdominal pain five days later.

“Probably the worst pain you could imagine,” she said. “But just having a doctor tell you we think it’s this, we think it’s this, having six diagnoses in three days was probably the worst.”

Kirkpatrick is one of six people who became ill after eating at the restaurant.

The sign on the door Tuesday said the restaurant was temporarily closed. Health investigators say they are still searching for the source.

“It’s scary to think you go out to a restaurant and order food, and they’re supposed to be the healthiest friendliest places, you would think. And you end up contracting an illness,” Kirkpatrick said.

Tragic: Indiana mom speaks out after toddler’s sudden E. coli death ‘Misdiagnosed five times’

Less than a week after he woke up feeling ill, 2-year-old Grayson Dunham was dead — the victim of an E. coli infection complication that took a grave turn.

e-coli-graysondunham_family_picture_139d18e7d0c0a23e98ad3c5c74f1d824-today-inline-large2xNow, his grieving mom is sharing his story hoping to spread awareness so that other families don’t have to go through a similar ordeal.

“It is a parent’s worst nightmare,” Kayla Dunham, 25, who lives in Sheridan, Indiana, told A. Pawlowski of Today. “He had never been sick… When you think of things happening, you think of severe illnesses like cancer or car accidents. You don’t think of E. coli.”

The family had been enjoying the summer, visiting a state fair, going to a petting zoo and eating out last month, when Grayson suddenly started vomiting and experiencing diarrhea on the morning of Aug. 10.

Doctors couldn’t settle on an exact cause, Dunham said. At first, the family was told it was stomach flu, then indications that the boy’s intestines may have been folded over each other, then possible problems with his appendix. As time went by, Grayson started having intense abdominal pain and bloody diarrhea.

“We were misdiagnosed five times before they said, yes this is HUS,” she recalled.

HUS, short for hemolytic uremic syndrome, can strike after an E. coli infection of the digestive system, according to the National Institute of Diabetes and Digestive and Kidney Diseases. It destroys red blood cells and clogs the kidneys’ filtering system. HUS is the most common cause of acute kidney injury in kids.

Grayson’s stool sample ultimately tested positive for Shiga toxin-producing E. coli, Dunham said. The family tried to figure out how he could have been infected: Was it the petting zoo? The restaurants they visited? Produce that his mom bought at a supermarket? The local health department told Grayson’s parents they may never know the source.

Grayson finally ended up in the intensive care unit of a children’s hospital in Indianapolis, Dunham said. Doctors told his parents he was stable for the night and urged them to take a nap in a nearby room, but the family was soon jolted by news the boy was deteriorating. His hemoglobin — a protein in red blood cells that carries oxygen — had dropped from the normal range to zero, his mom said.

Doctors were not able to get his heart pumping on its own and performed CPR for an hour and 45 minutes, but to no avail, she recalled. Grayson passed away at 4:30 in the morning on Aug. 15.

“My heart is in shock, I’m numb, and I don’t have words for what even happened,” Dunham wrote on Facebook. Doctors still don’t know why her son deteriorated so suddenly, she said.

10 sick: E. coli strain that closed Matador restaurant found elsewhere

JoNel Aleccia of The Seattle Times reports that an outbreak of E. coli O157:H7 that closed the Matador restaurant in Seattle’s Ballard neighborhood last week appears to be linked to more illnesses in Washington and three other states, health officials said Monday.

matador-seattleIn addition to the five illnesses linked to the Matador, two more Washington cases — one in Skagit County, one in Snohomish County — have been detected that have no connection with the Matador, a spokeswoman with the state Department of Health said Monday.

And three cases with the same genetic fingerprint have been detected in three other states, officials with the Centers for Disease Control and Prevention indicated. One of those people visited Seattle and ate at the Matador in Ballard.

That’s a total of 10 cases of what are known as STEC infections — but just six of those cases appear related to the restaurant.

Such dispersed illnesses indicate that the problem might not lie entirely with the Matador in Ballard. The restaurant closed Friday after inspectors with Public Health – Seattle & King County said they temporarily suspended the firm’s food business permit to allow thorough cleaning and sanitizing.

“It’s looking more like a potential source, a contaminated product,” said Dr. Meagan Kay, a medical epidemiologist with King County.

State and federal officials have taken over the probe, she added.

Restaurant owner Zak Melang, who runs 14 sites in several states, said the problem may lie with an outside vendor. He urged health officials to investigate quickly to clear his name.

“It’s our reputation on the line,” he said Monday. “The questions aren’t stopping.”

Since 2010, the Matador has been cited 10 times for food-handling practices linked to higher risks of food-borne disease, according to public-health records. Six of those violations were for failure to keep food at the proper cold holding temperatures, which keeps bacteria growth in check, the records show.

6 children sick: E. coli cases confirmed in Missouri

The Columbia/Boone County Department of Public Health and Human Services has confirmed four cases of Shiga toxin-producing E. coli O157:H7 , and two probable cases in Boone County preschool and school-aged children.

sorenne-hi-mommyPublic Health officials are reviewing laboratory analyses and conducting case interviews to determine the possible cause(s) of the outbreak. Currently, the source of the infection has not yet been determined.  

Tragically Chipotle: Freebies, settlements, falling stock and drones

It’s about having a voice.

Chipotle can hire all the food safety bigshots it likes, but it has no story, no narrative, to get past its five outbreaks in six months; and no amount of freebies are going to fix that.

kenny-diarrheaChipotle news is playing on the background of Mr. Robot. That’s prophetic.

Google parent company Alphabet is teaming up with Chipotle to test drone delivery for Virginia Tech students, according to a report from Bloomberg. The pilot program marks a turning point for Alphabet’s Project Wing division, giving the team ample room to experiment with airborne burrito deliveries in one of the first commercial programs of its kind to be greenlit by the US Federal Aviation Authority. The drones, which will be hybrid aircraft that can both fly and hover in place, will make deliveries coordinated by a Chipotle food truck on campus.

The news Chipotle probably wanted highlighted was that it has reportedly quietly settled nearly 100 claims over the last six months out of court, probably so the company won’t remind the public that they were so recently plagued by rampant food poisoning. The terms of the settlements are all confidential, but the claims were all filed by people whose ailments were verified by medical professionals. An attorney representing some of the plaintiffs called Chipotle’s move “textbook appropriate,” adding, “They’ve taken responsibility.”

“In 25 years of doing foodborne illness cases, I’ve never had a client ask for coupons for the restaurant they had gotten sick at,” said William Marler, an attorney with Seattle-based Marler Clark who represented 97 Chipotle customers. “In fact, some (clients) had gone back to the restaurant and they would call me and say, ‘Do you think it’s bad that I went back and got a burrito?’”

The company’s stock traded at $430.70 on Friday, down 1.3 percent, and lower than its 52-week high of $757 last October.

“They have a following of especially 20-somethings that other restaurants don’t have,” Marler said. “It’s a little odd, but it probably says something positive about Chipotle.

No, it says there’s a generation so much dumber than its parents.

But who am I to debunk an American myth.

Ironical that this video about American mythology was shot outside Melbourne. Chipotle blamed its E. coli outbreaks on Australian beef. Chipotle: local, fresh hypocrites.

 

New cheese alert after child’s E. coli death

A three-year-old girl from Dunbartonshire who died from E. coli O157 was among 20 confirmed cases that emerged in July and linked to Dunsyre Blue cheese made by South Lanarkshire-based Errington Cheese.

e-coli-o157-cheeseOn Saturday, Food Standards Scotland ordered the withdrawal from sale of batch G14 of Lanark White (unpasteurized) ewe milk cheese, adding, “A sample from a batch of Lanark White submitted for testing by South Lanarkshire Council has tested positive for E. coli O157. Although this organism may not carry shiga toxins, it is associated with human disease in the UK, so this cheese is a potential risk to health. FSS has issued a FAFA [Food Alert for Action] calling for this product to be immediately recalled from sale.”

The order to withdraw the cheese from sale was made after Errington refused to issue its own voluntary recall.

The company said the cheese had been on the market for three weeks with no reported cases of illness.

In a statement on its website, it said: “When we were told of the presumptive E. coli O157 result we immediately consulted experts in dairy microbiology.

“The experts told us they were confused and concerned by the testing methodology adopted by the laboratory.

“We have given careful consideration to this and to the fact that the cheese has been on the market for three weeks now with absolutely no reported incidence of illness.

“We have arranged for the sample of the same cheese tested by the authorities to be tested and the results will be ready on Monday when we will review the situation.”

Health Protection Scotland previously said that epidemiological investigations had “identified Dunsyre Blue cheese as the most likely cause of the outbreak”.

It added: “Despite extensive investigation, including looking for other possible food sources, no other link to a majority of cases could be established.”

Errington Cheese disputed the link, maintaining there was no conclusive evidence linking its products to the outbreak.

In a statement on its website last month it said that testing had shown it to be “completely clear of E. coli O157.”

Professor Hugh Pennington, the country’s leading expert on E. coli, told the Herald Scotland it could be difficult to identify it in any product suspected of causing food poisoning as by the time the illness comes to light, the food is usually all consumed or thrown away.

“Even if some of the batch (of food) is available for testing the bug might not be evenly distributed through a whole product, and so you might test part of the product that has been left or not been eaten yet and not find it – that doesn’t prove it wasn’t there in the bit that has been eaten,” he said.

“Scientifically it is sometimes quite complicated to come to a straightforward conclusion. The cheese manufacturers rightly say what is the evidence – but the regulatory authorities might never be able to come up with that.”

Joanna Blythman, investigative food journalist and the Sunday Herald’s food critic, said she believed there was a prejudice in Scotland against raw milk products, adding, “The (Dunsyre Blue) case puts a chill round everyone who wants to make a small scale artisan food. Meanwhile, the real prime suspects for large scale food poisoning are our industrial food producers.”

Stick to journalism. Illness per meal and type of food consumer and processing technique would have to be factored into any comparison of one food and artisan products.

5 sick: Seattle restaurant closed after links to E. coli

King County Public Health is investigating an outbreak of E. coli at the Matador restaurant in Ballard that sickened five people.

matador-seattleHealth officials said in all five cases, customers developed symptoms including diarrhea and abdominal cramps after eating at the restaurant late last month. Three of those people had to be hospitalized, and one of those patients developed a kidney problem. All five people have since recovered.

Laboratory tests determined all five people had the same strain of E. coli.

The restaurant has been temporarily closed while the health department investigates the cause of the contamination. The restaurant will also be thoroughly cleaned and sanitized.

To use antibiotics or not: E. coli O80:H2 in France

Jenina Pellegren of Contagion Live writes that Enterohemorrhagic Escherichia coli (EHEC) are a subset of Shiga toxin–producing E. coli (STEC) that cause diarrhea and hemorrhagic colitis. The illness can progress to hemolytic uremic syndrome (HUS) in 5%-10% of cases.

maxresdefaultIn France between 2005 – 2014, a total of 54 patients were infected with EHEC O80:H2; 91% had HUS. Two patients had invasive infections and 2 died. Similar strains were found in Spain with all isolates belonging to the same clonal group.  

“Azithromycin decreased Shiga toxin in subinhibitory concentrations significantly. Ciproflaxacin increased it substantially and ceftriaxone had no major effect. The occurrence of bacteremia during EHEC infections warranted antibiotic treatment. However, antibiotics are not usually recommended because of the risk for worsening HUS, notably by the secretion of Shiga toxin (Stx). This represents a therapeutic challenge.”  

In 2011, an outbreak in Germany linked to EHEC O104:H4 underscored the potential benefit of certain antibiotics when HUS occurs, making the use of antibiotics a source of debate. To determine the incidence rate of HUS cases associated with the singular EHEC O80:H2, a study examined the effects of different antibiotics on Stx production in representative strains.  

During January 2005 – October 2014 The Centre National de Reference Associe Escherichia coli, in France, collected 57 different strains of EHEC O80:H2. Isolated from stool specimens of over 54 patients; 2 and 3 isolates each were recovered from 2 patients.  

According to the Center for Disease Control and Prevention (CDC) “Among the 53 patients for whom clinical data were available, 49 (91%) had HUS; 27 (51%) were male. Median age for these 48 patients was 1.2 years (range 0.2–39 years, interquartile range [IQR] 0.7–1.6 years). Only 1 adult HUS patient (a 39-year-old) was reported. The 5 (9%) non-HUS patients were largely older (1, 2, 6, 21, and 40 years old). Among HUS patients, fever was present in 45%; median leukocyte count was 13,000 cells/mm3 (data were not available for 14 patients), and 56% had leukocytosis (>11,500 leukocytes/mm3).”  

Several studies demonstrated that the effect of antibiotics on HUS depends on their class.  Ciprofloxacin raises the production and release of Stx in vitro and is associated with a higher mortality rate in pigs. Yet, other studies indicate azithromycin might decrease the production and release of Stx. However, during a 2011 outbreak of EHEC O104 infection in Germany, a patient treated by ciprofloxacin plus imipenem unexpectedly had a better prognosis.  

Despite promising in vitro results, the authors of the study could not advocate the use of these antibiotics for treatment of patients infected with EHEC O80:H2. While potentially promising, these findings are preliminary and require confirmation.

Antimicrobial coatings could improve cantaloupe safety

Nicola Perry of Contagion Live writes that according to new research, applying antimicrobial coatings to whole cantaloupes during storage significantly reduces contamination by pathogenic bacteria, and has the potential to improve their microbiological safety and extend their shelf life.

cantaloupe-salmonellaQiumin Ma, PhD, from the University of Tennessee in Knoxville, and colleagues published the results of their study in the International Journal of Food Microbiology.   Chitosan-based coatings “significantly inhibited the growth of E[scherichia] coli O157:H7, L[isteria] monocytogenes and S[almonella] enterica cocktails on whole cantaloupes during 14-day storage at ambient temperature (21°C),” the authors write. “Coatings also significantly reduced total mold and yeast counts on whole cantaloupes.”   Cantaloupes are particularly susceptible to microbial contamination because they grow on the ground and can therefore come into contact with foodborne-pathogens associated with polluted irrigation water, uncomposted manure, or animal droppings. They can also become contaminated during harvesting, handling, and preparation. The rough cantaloupe skin also allows bacteria to easily attach to the surface of the fruit. 

“These pre- and post-harvest safety factors have directly or indirectly contributed to more than 25 outbreaks of foodborne illnesses associated with the consumption of cantaloupes between 1973 and 2003 in the United States and Canada,” the authors state.  

Food preservation, safety, and quality maintenance therefore represent mounting concerns for the food industry. Antimicrobial food coatings represent just one form of technology that has been investigated as a tool to help improve food safety in various food types, including fresh produce and meats.    

Chitosan, derived from the polysaccharide chitin, is known to have film-forming properties as well as antimicrobial activity. Chitosan-based coatings have also been shown to improve food safety—in fresh produce, for example.   With this in mind, Dr. Ma and colleagues conducted a study to investigate the efficacy of such antimicrobial coatings in reducing bacterial populations from the surface of cantaloupes. In addition to chitosan, they investigated two generally-recognized-as-safe antimicrobials—lauric arginate (LAE; which inhibits a broad spectrum of foodborne pathogens) and cinnamon oil (CO; an essential oil that has shown activity against Listeria species, gram negative bacteria, E. coli 0157:H7, and Salmonella species). They also investigated ethylenediaminetetraacetic acid (EDTA; an agent that chelates divalent calcium ions that are important to bacterial structures; it also enhances the activity of some antimicrobials).

Pathogens in raw sheep’s milk cheese

Italy is one of the main producers and exporters of cheese made from unpasteurized sheep milk. Since raw milk and its derived products are known sources of human infections, cheese produced from raw sheep milk could pose a microbiological threat to public health. Hence, the objectives of the study were: to characterize the potential risk of the presence of pathogens Escherichia coli O157, Listeria monocytogenes, and Salmonella in raw ovine milk destined for cheese production obtained from all the sheep farms (n = 24) in the Marches region (Central Italy) that directly transform raw milk into cheeses and to evaluate the equivalence between the analytical methods applied.

gene-wilder-sheepA three-step molecular method (simultaneous culture enrichment, species-specific DNA magnetic isolation, and multiplex real-time polymerase chain reaction) was used for milk (n = 143) and cheese (n = 5) analysis over a 3-year period. L. monocytogenes was not detected on any of the farms, while E. coli O157 was found on three farms, although only using the molecular method. Four farms tested positive for Salmonella spp., and Salmonella enterica subsp. diarizonae serovar 61:k:1,5,7 was isolated in one of those cases.

This information highlights the need to develop preventative measures to guarantee a high level of consumer safety for this specific product line, and the molecular method could be a time-saving and sensitive tool to be used in routine diagnosis.

Presence of Escherichia coli O157, Salmonella spp., and Listeria monocytogenes in raw ovine milk destined for cheese production and evaluation of the equivalence between the analytical methods applied

Foodborne Pathogens and Disease, ahead of print. doi:10.1089/fpd.2016.2159.

G Amagliani, A Petruzzelli, E Carloni, F Tonucci, M Foglini, E Micci, M Ricci, S di Lullo, L Rotundo, G Brandi

http://online.liebertpub.com/doi/abs/10.1089/fpd.2016.2159