Nolan Moittie was 23-months-old when he became one of 15 children in the Hauts-de-France region to fall ill having eaten beef contaminated with E. coli.
The boy was left paralysed for life, unable to walk, talk or eat.
Yesterday he was rushed to intensive care when his heart stopped beating.
He died shortly afterwards, despite medics’ efforts to revive him, Le Parisien reported.
The other children suffer from conditions that will affect their kidneys for the rest of their lives.
The lawyer of Nolan’s family, Florence Rault, said the boy had suffered a ‘real ordeal since the accident’.
Bosses at Seb-Cerf, who marketed frozen steaks under the Steak Country brand, were tried at Douai Criminal Court in northern France in 2017.
Former boss Guy Lamorlette, 78, was sentenced to three years in prison for failing to carry out checks on the meat.
He was also banned from any industrial or commercial activity and ordered to pay damages to the victims.
At a February hearing Lamorlette tried to blame Laurent Appere, the company’s former quality manager who died just before the trial began.
Lamorlette is said to be considering an appeal.
Nolan’s family lawyer, Florence Rault, told Le Parisien: “I hope that the person responsible for this tragedy will have the decency to withdraw his appeal on points of law.
“At the first trial, he did not even want to watch Nolan, now he must serve his sentence and Nolan’s parents must be able to be compensated and mourn.”