I love science: 28 sick from Salmonella in kratom

I go to group therapy most Fridays, because it keeps me humble.

Half are regulars, half are newbies, usually on some opioid path, of late.

The U.S. Centers for Disease Control along with public health and regulatory officials in several states, and the U.S. Food and Drug Administration (FDA) are investigating a multistate outbreak of Salmonella I 4,[5],12:b:- infections.

As of February 16, 2018, 28 people infected with the outbreak strain of Salmonella I 4,[5],12:b:- have been reported from 20 states. A list of the states and the number of cases in each can be found on the Case Count Map page. WGS performed on isolates from ill people were closely relatedly genetically. This means that people in this outbreak are more likely to share a common source of infection.

Illnesses started on dates ranging from October 13, 2017 to January 30, 2018. Ill people range in age from 6 to 67 years, with a median age of 41. Sixteen people are male. Eleven hospitalizations have been reported. No deaths have been reported.

WGS analysis did not identify any predicted antimicrobial resistance in isolates from five ill people. Testing of outbreak isolates using standard antibiotic susceptibility testing methods is currently underway in CDC’s National Antimicrobial Resistance Monitoring System (NARMS) laboratory.

Epidemiologic evidence indicates that kratom is a likely source of this multistate outbreak. Kratom is a plant consumed for its stimulant effects and as an opioid substitute. Kratom is also known as Thang, Kakuam, Thom, Ketom, and Biak.

In interviews, ill people answered questions about the foods they ate and other exposures in the months before they became ill. Eight (73%) of 11 people interviewed reported consuming kratom in pills, powder, or tea. No common brands or suppliers of kratom have been identified at this time.

At this time, CDC recommends that people not consume kratom in any form. The investigation indicates that kratom products could be contaminated with Salmonella and could make people sick. CDC’s recommendation may change as more information becomes available. This investigation is ongoing and we will provide updates as needed.

Multistate outbreak of salmonella I 4,[5],12:b- infections linked to Kratom

20.feb.18

CDC

https://www.cdc.gov/salmonella/kratom-02-18/index.html

36 dead: FDA says beware the herb kratom

The U.S. Food and Drug Administration has issued a strong warning to consumers to stay away from the herbal supplement kratom, saying regulators are aware of 36 deaths linked to products containing the substance.

Laurie McGinley of The Washington Post writes consumers are increasingly using the supplement, which comes from a plant in Southeast Asia, for pain, anxiety and depression, as well as symptoms of opioid withdrawal. The herb also is used recreationally because it produces symptoms such as euphoria.  Proponents say it is a safe way to deal with chronic pain and other ailments, and some researchers are exploring its therapeutic potential, including helping people overcome addictions.

But in a statement, FDA Commissioner Scott Gottlieb said that there is no “reliable evidence” to support the use of kratom as a treatment for opioid-use disorder, and that there are no other FDA-approved uses for kratom.

Rather, he said, evidence shows that the herb has similar effects to narcotics like opioids, “and carries similar risks of abuse, addiction and, in some cases, death.” He said that calls to U.S. poison control centers involving kratom increased tenfold between 2010 and 2015, and that the herb is associated with side effects including seizures, liver damage and withdrawal symptoms.