Japanese group wants to sell livers of toxic fish to diners

Prefectural government officials here are seeking permission to serve a delicacy they say will tantalize taste buds and bring in tourists. But restaurant operators across Japan say the plan could end up killing diners.

torafugu.pufferfishSaga Prefecture on the southern island of Kyushu has, according to The Asahi Shimbun, asked the health ministry to lift a ban on serving the liver of “torafugu,” the tiger pufferfish that carries a poison that is 1,000 times as toxic as potassium cyanide.

Prefectural officials say they have found a cultivation method and safety test system that can ensure the safety of pufferfish liver served at restaurants that meet certain conditions.

A nationwide association of 1,800 pufferfish restaurant owners and others disagree with that claim.

“If the prefecture’s proposal is approved, many consumers will mistakenly believe that pufferfish liver is safe to eat, resulting in more accidents,” said Yuichi Makita, 63, vice chairman of the association. “There is no absolute guarantee of safety.”

An expert panel on natural toxins and mycotoxins of the Food Safety Commission held a meeting on May 20 to discuss the prefecture’s proposal.

Food experts and biologists asked various questions, such as the reliability of the methodology to check the toxicity of the farmed pufferfish.

The commission is expected to decide on the proposal within a year.

The toxin of pufferfish is known as tetrodotoxin, and it is contained in the liver, ovaries and other organs, as well as in the skin and muscles.

Between 2006 and 2015, 356 people became ill after consuming pufferfish poison, and 10 of them died.

On May 24, eight people, including a restaurant manager, were arrested by Osaka prefectural police on suspicion of serving the liver of farmed torafugu, a violation of the Food Sanitation Law.

Osamu Arakawa, a professor of aquatic food hygienics at Nagasaki University who is familiar with pufferfish poison, said the toxin is produced from bacilli in seawater.

The toxic substance becomes concentrated in the bodies of pufferfish, which eat poisonous starfish and snails, he said. The possibility of the toxin accumulating in the fish through other channels has also been pointed out.

But a research team from Nagasaki University has surveyed 10,000 pufferfish raised with nontoxic food and confirmed that all of them were not poisonous.

Tragic: Japanese woman dies of sequela of E. coli poisoning 20 yrs after infection

In June 1996, initial reports of an outbreak of E. coli O157:H7 in Japan surfaced in national media.

radish_sproutsBy July 1996, focus had centered on specific school cafeterias and two vendors of box lunches, as the number of illnesses approached 4,000. Lunches of sea eel sushi and soup distributed on July 5 from Sakai’s central school lunch depot were identified by health authorities as a possible source of one outbreak. The next day, the number of illnesses had increased to 7,400 even as reports of Japanese fastidiousness intensified. By July 23, 1996, 8,500 were listed as ill.

Even though radish sprouts were ultimately implicated — and then publicly cleared in a fall-on-sword ceremony, but not by the U.S. — the Health and Welfare Ministry announced that Japan’s 333 slaughterhouses must adopt a quality control program modeled on U.S. safety procedures, requiring companies to keep records so the source of any tainted food could be quickly identified.

Kunio Morita, chief of the ministry’s veterinary sanitation division was quoted as saying “It’s high time for Japan to follow the international trend in sanitation management standards.”

Japanese health authorities were tragically slow to respond to the outbreak of E. coli O157:H7, a standard facilitated by a journalistic culture of aversion rather than adversarial. In all, over 9,500 Japanese, largely schoolchildren, were stricken with E. coli O157:H7 and 12 were killed over the summer of 1996, raising questions of political accountability.

The national Mainichi newspaper demanded in an editorial on July 31, 1996, “Why can’t the government learn from past experience? Why were they slow to react to the outbreak? Why can’t they take broader measures?” The answer, it said, was a “chronic ailment” — the absence of anyone in the government to take charge in a crisis and ensure a coordinated response. An editorial cartoon in the daily Asahi Evening News showed a health worker wearing the label “government emergency response” riding to the rescue on a snail. Some of the victims filed lawsuits against Japanese authorities, a move previously unheard of in the Japanese culture of deference.

Today, the sad news arrived that a 25-year-old woman in Sakai, Osaka Prefecture, died in last October of an aftereffect of her infection with E. coli O157 in 1996.

radish.sprouts.2The woman had been suffering renal vascular hypertension, a sequela of hemolytic-uremic syndrome she developed upon her infection with O-157 when she was a first-grade student, the city government said, adding the direct cause of her death was brain bleeding due to the hypertension.

Sakai Mayor Osami Takeyama said in a comment that the city will redouble efforts for safety control and crisis management.
 The municipal government now plans to provide compensation for the family of the woman.

The current version of events in July 1996, according to the Japanese, was 9,523 sick, including 7,892 elementary school children, in Sakai who ate school lunch or other food were infected with the E. coli bacteria. In the massive outbreak, three girls died.

 

E. coli hitching a ride in healthy Japanese food handlers

The actual state of intestinal long-term colonization by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli in healthy Japanese people remains unclear. Therefore, a total of 4,314 fecal samples were collected from 2,563 food handlers from January 2010 to December 2011.

tokyo-japan-shibuya-tokyu-food-show-depachika-600Approximately 0.1 g of each fecal sample was inoculated onto a MacConkey agar plate containing cefotaxime (1 μg/ml). The bacterial colonies that grew on each plate were checked for ESBL production by the double-disk synergy test, as recommended by the Clinical and Laboratory Standards Institute. The bacterial serotype, antimicrobial susceptibility, pulsotype, sequence type (ST), and ESBL genotype were checked, and the replicon types of plasmids harboring the ESBL gene were also determined after conjugation experiments.

ESBL producers were recovered from 70 (3.1%) of 2,230 participants who were checked only once. On the other hand, ESBL producers were isolated at least once from 52 (15.6%) of 333 participants who were checked more than twice, and 13 of the 52 participants carried ESBL producers for from more than 3 months to up to 2 years. Fluoroquinolone (FQ)-resistant E. coli strains harboring blaCTX-M were repeatedly recovered from 11 of the 13 carriers of blaCTX-M-harboring E. coli. A genetically related FQ-resistant E. coli O25b:H4-ST131 isolate harboring blaCTX-M-27 was recovered from 4 of the 13 carriers for more than 6 months. Three FQ-resistant E. coli O1:H6-ST648 isolates that harbored blaCTX-M-15 or blaCTX-M-14 were recovered from 3 carriers. Moreover, multiple CTX-M-14- or CTX-M-15-producing E. coli isolates with different serotypes were recovered from 2 respective carriers.

These findings predict a provable further spread of ESBL producers in both community and clinical settings.

Long-term colonization by blaCTX-M-harboring Escherichia coli in healthy Japanese people engaged in food handling

Applied and Environmental Microbiology; March 2016; vol. 82; no. 6; 1818-1827

Kunihiko Nakane, Kumiko Kawamura, Kensuke Goto and Yoshichika Arakawa

http://aem.asm.org/content/82/6/1818.abstract?etoc

Women more at risk than men of developing HUS from STEC E. coli in Japan

Shiga-toxin-producing Escherichia coli (STEC) infections usually cause hemolytic uremic syndrome (HUS) equally in male and female children. This study investigated the localization of globotriaosylceramide (Gb3) in human brain and kidney tissues removed from forensic autopsy cases in Japan.

e.coli.japanA fatal case was used as a positive control in an outbreak of diarrheal disease caused by STEC O157:H7 in a kindergarten in Urawa in 1990. Positive immunodetection of Gb3 was significantly more frequent in female than in male distal and collecting renal tubules.

To correlate this finding with a clinical outcome, a retrospective analysis of the predictors of renal failure in the 162 patients of two outbreaks in Japan was performed: one in Tochigi in 2002 and the other in Kagawa Prefecture in 2005.

This study concludes renal failure, including HUS, was significantly associated with female sex, and the odds ratio was 4·06 compared to male patients in the two outbreaks. From 2006 to 2009 in Japan, the risk factor of HUS associated with STEC infection was analyzed. The number of males and females and the proportion of females who developed HUS were calculated by age and year from 2006 to 2009. In 2006, 2007 and 2009 in adults aged >20 years, adult women were significantly more at risk of developing HUS in Japan.

Risk of hemolytic uremic syndrome caused by shiga-toxin-producing Escherichia coli infection in adult women in Japan

Epidemiology and Infection, Volume 144, Issue 5, April 2016, Pages 952-961, DOI: http://dx.doi.org/10.1017/S0950268815002289 

Fujii, T. Mizoue, T. Kita, H. Kishimoto, K. Joh, Y. Nakada, S. Ugajin, Y. Naya, T. Nakamura, Y. Tada, N. Okabe, Y. Maruyama, K. Saitoh, and Y. Kurozawa

http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=10216096&utm_source=Issue_Alert&utm_medium=RSS&utm_campaign=HYG

10 sick: E. coli O121 at childcare in Japan

Escherichia coli O121 has stricken 10 people — seven children between ages 2 and 6, a nurse and two parents — at an officially authorized childcare facility in Naha.

daycare_children_pictures_242_op_800x533According to the Okinawa Prefectural Office, after a 20-year-old nurse complained of symptoms including diarrhea, slight fever and stomachache, the cause was identified on Sep. 10 as the O121. A 4-year-old boy was confirmed of having the infection next to the nurse, and eventually 10 people developed the infection by of Oct. 2.

Good riddance: Raw pork liver fans say goodbye to banned sashimi in Japan

Fans of raw pork liver savored their last chance to taste the dish on Thursday night as they expressed mixed feelings on the arrival of a new food safety regulation Friday that bans eateries from serving pork sashimi.

raw.pork_.japan_“I often eat (pork liver sashimi) at yakiton (grilled pork) restaurants. I don’t know what I’ll do if I can’t eat it anymore,” said Hiromi Sasamoto, 33, as she downed the sashimi at Aji no Isohei, a pub in Tokyo’s Oimachi district.

“I always order this if restaurants have it on the menu,” said Shota Komukai, 31, who was with Sasamoto, adding that he likes the melting texture and sweetness of what is known locally as buta reba sashi.

A 42-year-old man who hadn’t eaten pork liver before said he came to taste it because Thursday was the last day to try it.

Compared with beef liver sashimi, “it tastes plainer. It’s delicious,” he said.

Restaurants said they got extremely busy serving the sashimi as the deadline approached.

Japan to ban restaurants from serving raw pork

The central government will ban restaurants from serving raw pork starting in mid-June, following a similar ban in 2012 on beef liver, the health ministry said Wednesday.

raw.porkRestaurants have increasingly turned to pork after the ban on raw beef liver.

The ministry said it would now require pork to be heat-sterilized to prevent food poisoning. It will also ban retailers from selling pork for raw consumption.

The Health, Labor and Welfare Ministry cited the possibility that pigs’ innards could be tainted with the hepatitis E virus, which causes liver inflammation, as the reason for the ban.

Under the new requirements, pork will have to be heated for at least 30 minutes at 63 degrees, or be heat-sterilized in other ways with a similar effect, the ministry said.

Violators will face up to two years in jail or a ¥2 million fine, it added.

The ministry will also urge consumers not to eat raw pork, saying the meat should be heated for at least a minute at 75 degrees.

The number of hepatitis E patients hit a record high of 146 in 2014 from 55 in 2011, with pork the most likely cause among foodstuffs, according to data compiled by the National Institute of Infectious Diseases.

Lost in translation: My way

In late November, 2014, I ventured off to Tokyo to do a week of shooting for a food safety documentary.

powell.japan.video.may.15 murray.lost.translationLike most TV, me and another dude, formerly of the UK Food Standards Agency, spent a lot of time sitting around and driving places, but it ended with a 2-hour documentary on food safety in Japan.

Here is the two-minute version.

And I had to do that airport entry-greeting 10 times before the director was happy, after going to the bathroom and changing into a suit after a 12-hour flight.

I had to buy a new suit, because I hadn’t worn one in 15 years.

 

 

Food safety style: The art of the Japanese company apology

Imagine you’re the head of a US fast-food chain in Japan that has been scandalized by a tooth-in-french-fries disaster. How do you repair the damage? Bow deeply — and be convincing.

belushi.samuriSo it was for Sarah Casanova, the Canadian president of McDonald’s Japan, whose less-than-textbook corporate mea culpa this month was an attempt at the tightly choreographed script routinely used by crisis-hit organisations.

With cameras rolling and reporters at the ready, apology press conferences are a must-do piece of theatre for Japanese firms that wandered from the straight-and-narrow in a country that has a dozen expressions for saying sorry.

Act 1: Wear dark colors, look grim and apologise profusely. Add a liberal sprinkling of words like “unfortunate” and “deeply regrettable”.

Act 2: Take a deep bow — better keep limber since you have got to make like a right angle or you will look like an amateur.

Act 3: Forget about buying a Porsche this year. You’ve got to cut your pay temporarily or forgo a bonus. Senior managers too.

Acts 4 and 5: Optional add-ons (depending on circumstances) — quit outright, or more likely step aside and put someone else in as CEO. Promise sweeping changes to avoid further scandals.

“This is part of a broader cultural phenomenon where the leader takes a hit for the team, then hopefully… society at large moves on,” says Jun Okumura, an independent analyst and visiting researcher at the Meiji Institute for Global Affairs.

Television and social media have made it all the more important to convince a Japanese public sensitive to visual cues, says Mitsuru Fukuda, a professor of crisis management and risk communications at Nihon University in Tokyo.

“A big difference is that in the West, facts matter,” he says.

“Japanese journalists… focus on top leaders’ apologies.”

Business communication specialist Yasuyuki Mogi adds: “Unless words of apology are at the forefront, many Japanese feel (it) lacks sincerity.”

But even a picture-perfect effort on Casanova’s part might not have helped much to make up for mounting losses and allay public concerns after a string of food scares, including the human tooth found in a box of french fries, says Jeff Kingston, a professor of Asian Studies at Temple University’s Tokyo campus.

“When you are in the business of selling food and your food is found wanting and considered unhealthy there is no bow low enough to right what is wrong.”

Five Japanese men poisoned by puffer fish after ‘eating highly poisonous liver’

Five men have been poisoned in Japan after allegedly asking a restaurant to serve them banned parts of the world’s most toxic fish.


puffer.fish.liverThe men were having dinner on Friday night in the western city of Wakayama when they ate puffer fish liver, which prompted vomiting and breathing difficulties early the next morning.

Puffer fish – also called blowfish or fugu in Japanese – are the world’s most toxic group of fish and their livers, ovaries and skin contain tetrodotoxin, 100 times more lethal than cyanide.

Yet eating the fish’s flesh is a tradition in Japan, where wealthy diners play the Russian roulette of the restaurant world by dining on sashimi slivers so thin they are almost transparent.

According to a city health official, the men asked to eat a banned, toxic part of the fish – which the most foolhardy fugu aficionados are said to enjoy for the tingling it produces on the lips.

The tingling is only the first symptom of tetrodotoxin poisoning, and is seen as part of the thrill for lovers of the fish.

But if the toxin is served in any significant quantity it then paralyses the muscles, suffocating victims as it reaches their chests and diaphragms while they are still conscious.

The health official said the men were in their 40s and 50s and the restaurant was shut down for five days from yesterday amid an investigation.