Cheech and Chong are back on the road and researchers in Italy and Britain have found that the main active ingredient in marijuana — tetrahydrocannabinol, or THC — and related compounds show promise as antibacterial agents, particularly against microbial strains that are already resistant to several classes of drugs.

The N.Y. Times reports,

“It has been known for decades that Cannabis sativa has antibacterial properties. Experiments in the 1950s tested various marijuana preparations against skin and other infections, but researchers at the time had little understanding of marijuana’s chemical makeup.

“The current research … looked at the antibacterial activity of the five most common cannabinoids. All were found effective against several common multi-resistant bacterial strains, although, perhaps understandably, the researchers suggested that the nonpsychotropic cannabinoids might prove more promising for eventual use.”